Effects of Collagen on Skin Aging

Various dietary supplements are claimed to have anti-aging properties on the skin; however, there are limited research studies to support these claims. The aim of this research is to examine the effectiveness of collagen hydrolyzate (CH), which consists of special collagen peptides, on skin biophysical parameters related to aging. In this double-blind, placebo-controlled study, 69 women aged 35-55 years were randomized to receive either 2.5 g or 5.0 g CH or placebo once daily for 8 weeks, and 23 subjects were assigned to each treatment group. Skin elasticity, skin moisture, transepidermal water loss and skin roughness were measured objectively before the first oral product administration (t0) and after 4 (t1) and 8 weeks (t2) of regular intake. Skin elasticity (primary interest) was also evaluated at follow-up 4 weeks after the last CH ingestion (t3, 4-week regression phase). At the end of the study, skin elasticity in both CH dosage groups showed a statistically significant improvement compared to placebo. After 4 weeks of follow-up treatment, a statistically significantly higher level of skin elasticity was determined in older women. Regarding skin moisture and skin evaporation, a positive effect of CH treatment can be observed in a subgroup analysis. No adverse effects were noted throughout the study.

https://pubmed.ncbi.nlm.nih.gov

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